产品货号：
Z17231
中文名称：
GRIK1抗体
英文名称：
Anti-GRIK1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GRIK1 Antibody |
| 指标别名 | EAA3;EEA3;GLR5;GluK1;GluR 5;GLUR5;Glutamate receptor 5;GRIK1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | GRIK1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Grik1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human Grik1.The immunogen is located within the last 50 amino acids of Grik1. |
| 计算分子量 | 104kDa |
| 成分 | Grik1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Grik1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes.Grik1,also known as glutamate receptor 5,belongs to the kainate family of glutamate receptors,which are composed of four subunits and function as ligand-activated ion channels.Grik1 is expressed in GABAergic interneurons of the hippocampus and are thought to participate in the formation of various subtypes of kainate receptors with Grik2 and KA2.Stimulation of Grik1 leads to intracellular calcium release and activation of protein kinase C.Excessive activation has been associated with psychiatric,neurological and neurodegenerative diseases.Numerous isoforms of Grik1 are known to exist and may be subject to RNA editing within the second transmembrane domain,which is thought to alter the properties of ion flow. |
| Uniprot ID | P39086 |
| 基因名全称 | Glutamate receptor,ionotropic,kainate 1 |
| 蛋白名全称 | Glutamate receptor,ionotropic,kainate 1 |
| 推荐稀释比 | Grik1 antibody can be used for detection of Grik1 by Western blot at 0.5 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples.All other applications and species not yet tested. |
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